Semler Scientific Targets 105,000 Bitcoin by 2027 in Bold Treasury Shift

Health tech firm Semler Scientific Inc. is making waves in the crypto space with an aggressive Bitcoin acquisition strategy—aiming to hold 105,000 BTC by 2027. This marks a staggering 28-fold increase from its current 3,808 Bitcoin holdings and could position the company as one of the largest corporate holders of Bitcoin globally.

Bitcoin Strategy Accelerates

In a strategic announcement on Thursday, Semler revealed a detailed roadmap for its Bitcoin accumulation:

• 10,000 BTC by end of 2025

• 42,000 BTC by end of 2026

• 105,000 BTC by end of 2027

To fund this ambitious expansion, the company plans to tap into a combination of equity offerings, debt financing, and operational cash flows.

Source: Eric Semler

Read More: Bitcoin Price Stagnates Below $112K Amid Global Uncertainty

Leadership for the Bitcoin Play

Driving this strategic shift is Joe Burnett, newly appointed as Director of Bitcoin Strategy. Burnett brings deep expertise from his time at Bitcoin-native firms like Unchained and Blockware Solutions, and formerly with Big Four firm Ernst & Young.

“The momentum behind Bitcoin adoption as a treasury asset is building rapidly,” said Burnett. His appointment signals Semler’s serious intent to embed Bitcoin at the core of its financial strategy.

Semler’s Holdings: A Growing Force in Corporate Bitcoin

Having first entered the Bitcoin space in May 2024, Semler has already accumulated over 3,800 BTC, making it the 13th largest public corporate holder according to BitBo. If it hits its 105,000 BTC target, it will hold 0.5% of Bitcoin's fixed 21 million supply.

Semler isn’t alone. Japanese investment firm Metaplanet recently set an even larger goal of 210,000 BTC by 2027, signaling a broader corporate trend of treating Bitcoin as a reserve asset rather than a speculative play.

Risks & Investor Sentiment

However, not everyone is convinced. VanEck crypto analyst Matthew Sigel cautioned that if a company's stock falls too close to its net asset value, it may risk shareholder dilution from aggressive at-the-market offerings.

Semler’s stock (NASDAQ: SMLR) has declined by 41% year-to-date, now nearing pre-Bitcoin strategy levels. Sigel remarked that Semler is “approaching parity,” implying that further Bitcoin purchases could be risky unless stock performance rebounds.

Source: Joe Burnett

Read More: Marathon Digital Becomes the Second-Largest Corporate Bitcoin Holder After Recent Acquisitions

Bitcoin Profits and Shareholder Exposure

Despite market skepticism, Semler's Bitcoin bets have paid off so far. As of June 3, the company had achieved a 287% return with an unrealized gain of $177 million.

It also ranks fourth in Bitcoin per share at 0.00034 BTC, based on data from BitcoinTreasuries.NET, reflecting significant Bitcoin exposure per shareholder.

Key Takeaways for Investors

• Semler’s Bitcoin strategy may position it as a long-term leader in the intersection of healthcare and digital assets.

• Shareholders now enjoy increased exposure to Bitcoin performance—but also face volatility risks.

• This bold move could influence other mid-cap firms to explore crypto treasury strategies.