Emerging Markets, AI, and Crypto: Insights from Ryze Labs’ Matthew Graham

At the Emergence Conference in Prague, Matthew Graham, the founder and CEO of Ryze Labs, shared his vision for the future of artificial intelligence (AI) and cryptocurrency. As a leading voice in these rapidly advancing sectors, Graham is committed to driving innovation by connecting talent with capital, particularly in emerging markets.
Based in Shanghai, Ryze Labs has established itself as a powerhouse in the investment landscape, supporting groundbreaking projects at the intersection of crypto and AI. The company’s portfolio spans diverse ventures, including alternative Layer-1 blockchains like Polygon and Sui, infrastructure projects such as LayerZero and Builders Tribe, and an array of decentralized applications (DApps), gaming platforms, and metaverse initiatives.
The AI-Crypto Intersection: A Game-Changing Wave of Innovation
Graham is particularly enthusiastic about the convergence of AI and blockchain technology. “In my view, the AI intersection with crypto and the tremendous innovation around that is the most important wave of innovation we’ve seen since DeFi summer,” he remarked. This synergy, he believes, holds immense potential for entrepreneurs and innovators in the blockchain space.
Earlier this year, Ryze Labs launched the AI Combinator in collaboration with a16z, aiming to create a hub for developers to explore and accelerate progress in AI and blockchain. The incubator, backed by a $5 million fund, has already supported 10 to 12 projects at this intersection, signaling strong confidence in the sector’s transformative potential.
Strategic Investments in Blockchain Ecosystems
Ryze Labs has made significant investments in the Solana ecosystem, acquiring MNDE tokens through Marinade, Solana’s leading staking protocol. This move reflects the company’s confidence in Solana’s SVM framework and its potential in staking advancements and PayFi applications. Additionally, Graham’s investment in the TON blockchain leverages Telegram’s 900-million-strong user base, positioning it as a foundation for building next-generation Web3 super apps.
“The possibilities of AI in crypto are vast, ranging from automating tasks to creating AI agents that influence and inspire real-world human actions,” Graham explained. He envisions a future where AI operates as a middle layer atop multiple Layer-1 blockchains, facilitating seamless interaction across ecosystems rather than being confined to a single blockchain.
Empowering Emerging Markets
Emerging markets represent a focal point for Ryze Labs. Graham believes these regions hold the key to the next wave of blockchain users and developers. “These markets are where the next wave of users and builders will come from,” he stated, emphasizing the importance of providing tailored support to navigate unique regulatory, cultural, and technological landscapes.
Ryze Labs has turned its attention to global hubs like Lagos and Bangalore to identify talent and uncover the next AI-crypto unicorns. Graham highlighted the role of cultural narratives and internet lore in uniting communities across geographic boundaries, describing these elements as critical to the success of innovative projects.
Fostering Creativity Through AI Agents
A striking example of this creative convergence is the Terminal of Truths, an AI agent founded by Andy Ayrey. This project, which integrates internet memes with Solana’s blockchain, gained attention after receiving $50,000 in funding from a16z’s Marc Andreessen. Graham described this moment as a turning point in his understanding of AI’s potential within the crypto ecosystem.
“Ultimately, our goal is to back the hell out of people building the most exciting projects at the intersection of AI and crypto,” Graham said. He remains steadfast in his belief that the convergence of AI and blockchain is not merely a trend but the next frontier of technological innovation.
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